Clinical Validation: Peer-Reviewed Study Results
Connected Mind was built on peer-reviewed clinical evidence — not marketing claims. Here is the study, the methodology, and the results. See how these findings translate into real-world features for your practice.
Connected Mind's screening achieves 96.4% Negative Predictive Power in peer-reviewed clinical validation published by Springer. This means when the screening stage indicates a patient is unlikely to have a condition, that result is correct 96.4% of the time. Conditions that screen positive proceed to Standardized Assessment Modules (SAMs) for further testing.
The Validation Study
Connected Mind's screening approach was evaluated in a peer-reviewed study published by Springer. The study assessed the clinical utility of the multi-condition behavioral health screening tool in real-world primary care settings.
Patients Enrolled
Independent Primary Care Practices
Conditions Screened Simultaneously
Study Design and Methodology
The validation study enrolled 234 consecutive patients across 5 independent primary care practices, representing a range of demographics, clinical presentations, and practice settings. Participants completed the Connected Mind screening as part of their routine visit, and results were compared against established gold-standard instruments administered independently by trained assessors.
Each patient was evaluated using the SCID-5-RV (Structured Clinical Interview for DSM-5) as the primary diagnostic reference, supplemented by condition-specific instruments: the PHQ-9 for depression, GAD-7 for anxiety, ASRS for ADHD, MDQ for bipolar disorder, AUDIT/DAST for substance use, and PHQ-15 for somatic symptoms. The study measured negative predictive power, sensitivity, and specificity across all 6 conditions to assess the tool's clinical utility as a broad screening instrument.
The multi-site design ensured that results were not skewed by a single practice's patient population or clinical workflow. Results were published in a peer-reviewed Springer journal, the Journal of Clinical Psychology in Medical Settings.
Negative Predictive Power
In a peer-reviewed study of 234 patients across 5 independent primary care practices, Connected Mind's screening stage achieved 96.4% negative predictive power — meaning when the screening indicates a patient is unlikely to have a given condition, that result is correct 96.4% of the time.
What is negative predictive power? NPP measures how reliably a negative screening result corresponds to a true negative. This metric applies to the screening stage. Conditions that screen positive proceed to SAMs, which have separate sensitivity and specificity profiles.
Positive screens automatically proceed to Connected Mind's validated Standardized Assessment Modules (SAMs) for confirmatory testing, where sensitivity, specificity, and positive predictive power vary by condition.
Individual results may vary based on patient population, clinical context, and implementation. Connected Mind is an informational tool designed for use by licensed healthcare professionals. It does not provide clinical interpretations, diagnoses, or treatment recommendations. All results require independent review by a qualified provider.
Validation Methodology
Connected Mind's screening results were validated against established, well-recognized clinical instruments. This multi-instrument comparison demonstrates that the tool performs comparably to or better than running multiple single-condition screeners separately.
Each instrument listed below is a widely adopted, peer-reviewed tool used in clinical practice and research. By comparing Connected Mind's results against all of them simultaneously, the validation study demonstrates that a single 8-question screening can provide coverage equivalent to administering these instruments individually — in a fraction of the time.
Read the Published Study
Clinical Utility of a Behavioral Health Screening Measure in Primary Care
Published by Springer · Journal of Clinical Psychology in Medical Settings
View on SpringerFrequently Asked Questions
Is Connected Mind clinically validated?
Yes. Connected Mind was validated in a peer-reviewed study published by Springer in the Journal of Clinical Psychology in Medical Settings. The study enrolled 234 patients across 5 independent primary care practices. Each participant was evaluated using the SCID-5-RV (Structured Clinical Interview for DSM-5), a gold-standard clinical interview administered by trained assessors, as the primary reference criterion.
What was the study size?
The validation study enrolled 234 patients across 5 independent primary care practices, representing a range of demographics and clinical presentations. Results were published in a peer-reviewed Springer journal, the Journal of Clinical Psychology in Medical Settings.
What is negative predictive power?
Negative Predictive Power (NPP) measures how often a negative screening result is correct. Connected Mind's screening stage achieved 96.4% NPP, meaning when the screening indicates a patient is unlikely to have a condition, that result is correct 96.4% of the time. Conditions that screen positive proceed to Standardized Assessment Modules (SAMs), which have their own sensitivity and specificity profiles.
What instruments was it validated against?
Connected Mind was validated against established gold-standard instruments including the PHQ-9 (depression), GAD-7 (anxiety), ASRS (ADHD), MDQ (bipolar), AUDIT/DAST (substance use), and PHQ-15 (somatic symptoms).
Where was the study published?
The validation study was published in the Journal of Clinical Psychology in Medical Settings, a peer-reviewed Springer journal. The full paper is available at doi.org/10.1007/s10880-021-09820-1.
What is the SCID-5-RV?
The SCID-5-RV (Structured Clinical Interview for DSM-5 — Research Version) is considered a gold-standard method for evaluating mental health conditions. It is a structured clinical interview administered by trained clinicians and was used as the primary reference criterion in the Connected Mind validation study.
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